Cancer is a multifactorial disease, which means it has many causes ranging from smoking habits to unhealthy lifestyles. One of the male sex hormone androgen which also increases the risk of cancer, especially liver cancer. Researchers from the Chinese University in Hong Kong recently discovered trigger liver cancer in men. One of the male sex hormone androgen in the liver lead to gene mutations that can develop into cancer through a particular mechanism.
The mutated gene is Cell Cycle-Related Kinase (CCRK), which is controlled by the male hormone androgen activity. The more the structure of DNA (Deoxyribo Nucleic Acid) on CCRK are mutated, the greater the role of androgens in triggering liver cancer.
'This finding explains why for this liver cancer occurs more frequently in men than in women,' said a genetics expert who was involved in research tersbeut, Mok Hing-Yiu as quoted from Straitstimes, Thursday (07/21/2011).
According to estimates by the World Health Organization or WHO, sex is associated with the risk of some types of cancer especially liver cancer. In the same general condition, men have three times higher risk than women to get liver cancer.
Disclosure of other factors that trigger liver cancer believed to be very useful in prevention efforts, given the death rates from liver cancer is very high. Currently, liver cancer is in the order of the three most deadly type of cancer after lung cancer and colon cancer.
Certain regions such as China and Japan have a number of cases of liver cancer is higher than other areas and until now not known exactly why. While in the United States, liver cancer affects 19,000 people / year with 17,000 deaths / year.
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