Bivalirudin is a drug that keeps blood platelets from clotting (clotting) to prevent unwanted blood clotting, which can occur with heart conditions and certain blood vessels.
Indications:
Used to prevent blood clotting in people with angina or other conditions who undergo a procedure called angioplasty (to open a closed artery).
Dosage:
1. 750 NCG / kg IV followed by infusion of 1.75 mg / kg / hour during the procedure, up to 4 hours after the procedure.
2. If needed, may continue infusion at doses of 0.2 mg / kg / hour, up to 20 hours.
Side Effects:
Haematological effects (bleeding); Effect Dermatology (hypersensitivity reaction, pain at the injection site, severe anaphylaxis); CV effects (hypertension, hypotension, bradycardia); Securities GI (N / V, dyspepsia); effects on the kidneys (urine storage); Muskoskeletal effects (back pain); CNS effects (headache, anxiety).
Special Instructions:
1. contra indications in patients with active bleeding, acute renal impairment including dialysis dependent patients.
2. Use caution in patients with high bleeding risk, the new operation, leakage of blood vessels or organs, biopsy, liver dysfunction and renal damage was.
No comments:
Post a Comment